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Can’t live without them! From Ashley Tisdale and Vanessa Hudgens to Brad Pitt and George Clooney, these celebrity best friends have stuck by each other side’s through thick and thin.

Tisdale and Hudgens formed a lasting bond while working together on several projects. The Suite Life of Zack and Cody alum played Sharpay Evans to the Spring Breakers star’s Gabriella Montez in 2006’s High School Musical, 2007’s High School Musical 2 and 2008’s High School Musical 3: Senior Year.

Their friendship continued long after the cameras stopped rolling, despite their onscreen alter-egos’ rivalry in the trilogy. “We just have a connection and she’s so awesome and one of my best friends,” Tisdale told Us Weekly exclusively in August 2019. “What I love about her is that she’s so talented, and I think what we share is that we’re really grounded people and I think that that’s important, especially with what we do, is to stay grounded.”

The “Voices in My Head” singer pointed out that their relationship goes further back than their Disney Channel days. “We actually worked together a year before in a Sears commercial, and from that day on we were super close,” she explained. “So people don’t really know — I think some people know that, but they think it was that movie that brought us together and it really wasn’t.”

Busy Philipps, for her part, revealed how she maintains her friendship with Michelle Williams years after the pals starred together on Dawson’s Creek. “Whether you’re, like, in the public eye or not, I think the secret to longevity in friendships is putting in the time and the understanding and working through any issues that might arise,” the Cougar Town alum shared exclusively with Us in June 2019. “I think that especially now with texting, it’s even easier to stay in touch with people and be communicative.”

Scroll through to see which A-listers consider one another their BFFs!


Melissa McCarthy and Octavia Spencer

The actresses formed their friendship in the '90s and have continued to keep that bond strong over the years. McCarthy and Spencer even took their close connection to the big-screen when they starred together in Netflix's Thunder Force in 2021. The film follows the pair as two lifelong best friends who become superheroes after they take a special serum.

"After 20+ years, I'm #stillbestfriends with the incredible @octaviaspencer and I wouldn't have it any other way ❤️" McCarthy captioned a compilation of photos of the duo in April 2021.

Courtesy Melissa McCarthy/Instagram
Reese Witherspoon and Laura Dern

The actresses became close friends after starring in 2014’s Wild and going on a press tour together to promote it. “You know someone is your favorite person when you’ve done a day of press, listened to yourself ad nauseam, listened to them tell every story, and when it ends, it’s like, ‘Are we going to eat something?’” Dern said of the experience in an interview with Vanity Fair. The two have since worked together on Big Little Lies, often go hiking together and in 2020 Witherspoon gave Dern tips on how to drink tequila during an Instagram Live chat.

Jordan Strauss/Invision/AP/Shutterstock
Cole Sprouse and KJ Apa

After meeting on the set of Riverdale in 2017, the New Zealand native and Disney Channel alum have become very close. They’ve traveled together, trolled each other via social media and Sprouse has photographed Apa as part of his passion for photography. In 2020, the two started quarantining together amid the coronavirus pandemic at Apa’s place in L.A. “I heard they’re just lifting weights and eating cheese,” Sprouse’s twin brother, Dylan Sprouse, told Entertainment Tonight in May 2020 about the duo’s living situation. “I think that’s what they do.”

Matt Baron/Shutterstock
Brad Pitt and Leonardo DiCaprio

It wasn’t until 2019’s Once Upon a Time in Hollywood that this duo acted alongside one another, but the bromance it created is already stuff movies are made of. During Pitt’s numerous awards show acceptance speeches in 2020, he showed how much he loves DiCaprio. “I also have to thank my partner in crime, LDC,” the Fight Club star said at the Golden Globes when accepting the award for Best Supporting Actor in a Motion Picture. “He’s an all-star, he’s a gent. I wouldn’t be here without you, man. I thank you, still.”

Eric Charbonneau/Shutterstock
Anna Camp and Brittany Snow

Not only have Camp and Snow played onscreen BFFs in three Pitch Perfect installments, but off screen they’ve become inseparable. Ahead of Camp’s wedding to Skylar Astin in 2016 (the two have since split), Snow celebrated her friend in style at a country-themed bachelorette bash. When Snow married Tyler Stanaland in March 2020, Camp was one of her many aca-awesome costars to attend the Palm Springs bachelorette party and California-based nuptials.

Jordan Strauss/Invision/AP/Shutterstock
Sophie Turner and Maisie Williams

The Game of Thrones costars bonded on the set of the HBO hit, which ran from 2011 to 2019. Williams even served as Turner’s maid of honor when the Dark Phoenix star married Joe Jonas in France in June 2019. The onscreen sisters also got matching tattoos in September 2016.

Joel C Ryan/Invision/AP/Shutterstock
B.J. Novak and Mindy Kaling

The former Office castmates dated before deciding to stick to friendship. “B.J. is so much more like family now than a platonic friend,” Kaling told GoodHousekeeping.com in May 2019. “He’s the godfather to my daughter [Katherine].”

John Salangsang/Variety/Shutterstock
Tina Fey and Amy Poehler

The comedians tackled pretty much everything together. Not only did they star on Saturday Night Live (including taking their turns at the "Weekend Update" desk), but they also went on to share the big screen in Sisters and Baby Mama as well as cohost the Golden Globes in 2013, 2014 and 2015.

Broadimage/Shutterstock
Jennifer Lopez and Leah Remini

Lopez and Remini became fast friends after being introduced by the singer’s ex-husband Marc Anthony in 2004. The pals later costarred in the 2018 film Second Act.

Jordan Strauss/Invision/AP/Shutterstock
Matt Damon and Ben Affleck

The childhood friends tackled Hollywood together, co-writing and acting in the Oscar-winning Good Will Hunting. Affleck and Damon remained besties long after their big break.

Jim Smeal/Shutterstock
Nina Dobrev and Julianne Hough

The Vampire Diaries alum told E! News in 2013 that she and the former Dancing With the Stars pro have been “connected at the hip” since their hairstylist, Riawna Capri, introduced them. Dobrev was later a bridesmaid for Hough at her July 2017 wedding to Brooks Laich.

Andreas Branch/Variety/Shutterstock
Jennifer Lawrence and Adele

In March 2019, the actress and singer had a raucous time during a girls' night out in New York City. The duo visited a West Village gay bar, and a source told Us, “Adele was on stage playing a game called Musical Shots. Jennifer Lawrence was in the audience cheering them on.” This wasn't the first time the friends were caught hanging out. In January 2015, the Oscar winner and the "Hello" songstress chatted after they bumped into each other at a restaurant in West Hollywood. “They exchanged a bunch of laughs for quite a while before Adele rejoined her table,” a source told Us at the time.

Later that year, the Grammy winner and the Red Sparrow star grabbed dinner together at a New York City restaurant with another of Lawrence’s celeb BFFs Emma Stone.

MEGA
Busy Philipps and Michelle Williams

Philipps met best friend Williams in 2001 after joining the cast of Dawson’s Creek and traveling to the show’s set in Wilmington, North Carolina. “I met you the first night I was there,” Philipps recalled when she hosted her former costar on a February 2018 episode of Busy Tonight. “I had been prepped that we were going to love each other, so it felt very high stakes, and we ended up immediately loving each other.”

Jordin Althaus/E! Entertainment
Reese Witherspoon and Chelsea Handler

"She's a really great friend. She's the kind of person who will cancel all her plans if you're in a bad mood and you just want to sit on the couch and watch a movie," Witherspoon says of Handler, who is also pals with Jennifer Aniston and Charlize Theron. "She's really generous. She likes to give a lot of good gifts!"

Jason Merritt/Getty
Jamie-Lynn Sigler and JoAnna Garcia

First-time moms Sigler, Garcia, and Jenna Dewan have all traded parenting tips in the time since giving birth in 2013. "It'll be so fun to do mommy groups and things together and use each other's experiences to learn." Sigler, mom to son Beau, predicts that he'll have quite a bit of face time with her friends' daughters Emerson and Everly. "He's going to have a little harem of princesses to choose from," jokes Sigler. "We all joke about it."

Thos Robinson/Getty
Beyoncé and Gwyneth Paltrow

These two powerhouse moms have bonded over protecting their daughters Blue Ivy and Apple. In 2013, Paltrow called Beyoncé “incredible” and said, "She's a great friend on every level."

Kevin Mazur/Getty Images
Miley Cyrus and Kelly Osbourne

Osbourne has stuck by her good friend Cyrus' side for years — even when her one-time Fashion Police co-host Joan Rivers blasted the "Wrecking Ball" singer. Osbourne told The Huffington Post in 2014 that she's "proud of her because whether you agree with what she does or not, she stands by her guns and she's not fake.”

Kevin Mazur/WireImage
Ashley Tisdale and Vanessa Hudgens

BFFs since their Disney days in High School Musical, Tisdale once gushed to Yahoo’s OMG! that “She's like my family. She's like my sister. We grew up together.”

Christopher Polk/Getty Images
Taylor Swift and Jaime King

After bonding at a Golden Globes party in 2014, the two blondes became fast friends. “She's the most fun, most loving, most wonderful and most generous friend and I feel very blessed to have her in my life," King has said of the songstress.

Michael Kovac/Getty Images
Kathie Lee Gifford and Hoda Kotb

These besties do everything from work together every day as co-hosts on Kathie Lee & Hoda to celebrate each other’s birthdays offscreen. When they first met, Gifford once told NBC, “I knew that day that even if we never worked together, she'd be my friend for the rest of my life." While Kotb added, "We have lunch together, we hang out, we talk on the phone... I confide in her, she confides in me. It's what a friendship is."

Peter Kramer/NBC/NBC NewsWire
Lauren Conrad and Lo Bosworth

"I have really gotten a chance to see who my true friends are and who is going to be there for me," Hills alum Conrad, who has based characters in her L.A. Candy books on her best pals, has said of those close to her, including former costar Bosworth.

Jon Kopaloff/FilmMagic
Kendall Jenner and Hailey Baldwin

Jenner and Baldwin have clearly bonded over their love for modeling and selfies. The BFFs have done everything together from take snaps in their Calvin Klein underwear to don matching leopard print bikinis.

Courtesy of Kendall Jenner
Brad Pitt and George Clooney

In an interview with The Hollywood Reporter in 2012, Clooney explained his longtime friendship with his Ocean’s Eleven costar Pitt. “Brad is one of the great guys,” he said. “We’re good friends, but it’s different from what people think, meaning we don’t spend a lot of time together. He has been to my home in Como; we motorcycle together. But [sometimes I don’t see him often].”

Christopher Polk/Getty Images
Khloé Kardashian and Rob Kardashian

They might be a family of six kids but Khloé and younger brother Rob’s bond is stronger than blood. Not only have these two decided to live with one another, Khloé publicly defended Rob when his ex Adrienne Bailon called him out for cheating. Khloé retweeted Kim Kardashian's tweet which read: "So sad when people try to kick my brother when he is down #FamilyForever."

Courtesy of Khloe Kardashian
Jaden Smith and Kylie Jenner

Once the subject of dating rumors, Jenner and Smith are simply platonic pals, and great ones at that, the Keeping Up With the Kardashians star explains. "He makes me laugh and he is a great dancer," Jenner raved to Seventeen of her "best guy friend.".

Steve Granitz/WireImage.com
John Stamos and Lori Loughlin

They were onscreen lovers on the hit '90s sitcom Full House, and its Netflix revival, Fuller House, to this day, TV's Rebecca Donaldson and Jesse Katsopolis remain pals. "I consider him one of my best, dearest friends," the actress gushed to Us of Stamos. "Certainly one of my oldest longtime friends."

L. Cohen/WireImage.com
Nikki Ferrell and Andi Dorfman

Ferrell credits Dorfman with helping her make it through their mutual 2014 stint on The Bachelor. "I could not have made it through this experience without you," pediatric nurse Ferrell recently wrote in a sweet Instagram note to her pal that accompanied this photo. "Thank you for being a best friend, someone I can always trust, laugh with, and cry with."

Courtesy of Nikki Ferrell
Ramona Singer and Sonja Morgan

Costars on Bravo's The Real Housewives of New York City, Singer and Morgan have seen each other through the best — and worst — of times. "We are like sisters now," Morgan —  who supported Singer through her split from husband Mario in 2014 — has told Andy Cohen. "We have the best times together. So many, and you can't count them."

Dave Kotinsky/Getty
Jennifer Aniston and Courteney Cox

"I can tell you we're both very fortunate to have each other," Cox told Marie Claire magazine.

Lester Cohen/WireImage.com
Jenni “JWoww” Farley and Nicole “Snooki” Polizzi

Developing a deep bond while shooting MTV's Jersey Shore, the duo have their own spin-off reality series and compare their friendship to TV BFFs Laverne and Shirley. "I think I'd be Laverne," Farley has said. "Shirley is more like a worrywart. Well, it depends on the episode." Polizzi take? "Whoever is the tall one, that one is Jenni."

Jim Spellman/WireImage.com
Kim, Khloé, and Kourtney Kardashian

"We're friends because we're sisters but I think we rotate on which one's our best friend," Khloé has said of her bond with Kim and Kourtney.

Denise Truscello/WireImage.com
Jennie Garth and Tori Spelling

After 10 years of sharing the same zip code on Beverly Hills, 90210, the actresses still support one another. The Peach Pit pals will reunite on TV when they produce and costar in ABC Family's Mystery Girls. "[The show] was just the perfect vehicle for me and Jennie. I just thought it would be a great thing for us to do together," Spelling tells Us.

Jeffrey Mayer/WireImage.com
Jessica Simpson and CaCee Cobb

First-time mom Cobb — who parents Rocco with husband Donald Faison — is getting parenting tips from her BFF Simpson. "She's got me beat," Cobb tells Us of Simpson, mom to daughters Maxwell and Birdie and son Ace. "Just watching her, I'm in awe because she makes it look easy — but it's not, I can tell!"

Larry Busacca/Getty
Zach Braff and Donald Faison

Costarring on the medical comedy Scrubs from 2001 to 2010, the pair remain close to this day. Braff — the godfather to Faison's son Rocco — invited his BFF and CaCee Cobb to hold their December 2012 wedding at his home.

Dave M. Benett/Getty
Jay-Z and Chris Martin

The rapper and Coldplay frontman collaborated on Jay Z's 2006 album Kingdom Come and the track Beach Chair.

Kevin Mazur/WireImage.com
Katy Perry and Rihanna

Though the pair reportedly had a falling out over Rihanna's relationship with Chris Brown, Perry couldn't help but take a playful jab at her pal during a 2013 chat with Elle Canada. "I think that Rihanna always looks so fresh and I'm like, 'How do you do that? We all know how much pot you smoke! And you don't sleep because you're on Instagram at four o'clock in the morning!'" she said with a laugh and a wink, calling out Rihanna's unapologetic marijuana use and selfie-prone tendencies.

Kevin Mazur/WireImage.com
Drew Barrymore and Cameron Diaz

Enlisting pal Diaz to help with her final wedding dress fitting and read a sweet poem at her May 2012 ceremony, Barrymore wasn't the first to know that Will Kopelman was planning to propose. "I knew Drew was getting married before she did!" Diaz told InStyle UK of her longtime BFF and Charlie's Angels costar.

Ryan Miller/Getty
Kathy Griffin and Cher

The comedienne and music legend have become such besties that they often have slumber parties at Cher's opulent California mansion. "Typically Cher demands a no makeup, sweatpants kind of situation for our nights in but on a recent visit, just to annoy her, I said, 'Will you do my makeup for me? Oh and make it sparkly,'" Griffin recalled in 2012. "After a quick argument she said, with no irony, 'Well we'll have to start in my sparkle drawer,' I immediately ran into her colossal Balinese themed bathroom to find the 'sparkle drawer.'"

Lester Cohen/WireImage.com
Lea Michele and Kate Hudson

Hudson has supported Michele in immeasurable ways since the July 2013 passing of Michele's boyfriend Cory Monteith. Chief among them: She opened her home up to Michele to hide out. "There's so many different emotions and to kind of have people watching every step of the way. But to have that time at [Hudson's] home to just really be in private with this for a moment — before getting back to work and before going home — I'm just so thankful to her," Michele has said.

Kevin Winter/Getty


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